Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325173 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL2145779 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL17620185 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL299362 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL9750672 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10821105 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL6137641 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL244255 | 0.78 | ALDH1A1 (0.76) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8507216 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL2309900 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060880-A1 | AMINOALKYL THIAZOLE DERIVATIVES AS KCNQ MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |