Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335641 | 0.85 | LTA4H (0.37) | KMT2AHDAC1HDAC2HDAC8 | |
| SCHEMBL9335520 | 0.81 | CYP2C9 (0.45) | CYP2C9CYP2C19SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9866700 | 0.80 | ITGB3 (0.38) | CYP2C9CYP2C19SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9335577 | 0.75 | CYP2C9 (0.56) | CYP2C9CYP2C19SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9335585 | 0.73 | CYP2C9 (0.53) | CYP2C9CYP2C19SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL21408504 | 0.71 | POLB (0.44) | SMN1; SMN2L3MBTL1POLBKMT2AMAPT | |
| SCHEMBL21408505 | 0.71 | POLB (0.44) | SMN1; SMN2L3MBTL1POLBKMT2AMAPT | |
| SCHEMBL2905983 | 0.70 | HDAC1 (0.33) | HDAC1HDAC2HDAC6 | |
| SCHEMBL5298045 | 0.70 | CA14 (0.31) | HDAC1HDAC2HDAC6 | |
| SCHEMBL991813 | 0.70 | HDAC1 (0.36) | L3MBTL1HDAC1HDAC2HDAC6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |