Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.39 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866887 | 1.00 | DRD4 (0.39) | DRD4DRD2ADRA2AADRA2BADRA2C | |
| SCHEMBL9866221 | 0.71 | KDM4E (0.33) | KDM4ENPC1TP53PKMRAB9A | |
| SCHEMBL9866219 | 0.71 | KDM4E (0.33) | KDM4ENPC1TP53PKMRAB9A | |
| SCHEMBL9865567 | 0.67 | DRD2 (0.33) | DRD4DRD2NPSR1 | |
| SCHEMBL9579238 | 0.63 | MAOA (0.38) | KDM4ENPC1TP53PKMRAB9A | |
| SCHEMBL9864852 | 0.63 | — | — | |
| SCHEMBL9864859 | 0.63 | — | — | |
| SCHEMBL10665534 | 0.63 | MAOA (0.38) | KDM4ENPC1TP53PKMRAB9A | |
| SCHEMBL4103085 | 0.60 | KDM4E (0.42) | DRD2KDM4ENPC1TP53PKM | |
| SCHEMBL8011197 | 0.60 | DRD4 (0.41) | DRD4DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | claimed |
| US-4992090-A | Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |