Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9868486 | 0.96 | SIGMAR1 (0.53) | SIGMAR1HTR1AL3MBTL1HTR7DRD2 | |
| SCHEMBL9867662 | 0.92 | HTR1A (0.57) | SIGMAR1HTR1AL3MBTL1PARP1 | |
| Oxalic Acid SCHEMBL9867184 | 0.89 | HTR1A (0.54) | SIGMAR1HTR1AL3MBTL1PARP1 | |
| SCHEMBL9868497 | 0.86 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR7DRD2PARP1 | |
| SCHEMBL9867975 | 0.86 | HTR1A (0.49) | SIGMAR1HTR1AHTR7DRD2PARP1 | |
| Oxalic Acid SCHEMBL9867718 | 0.84 | SIGMAR1 (0.50) | SIGMAR1HTR1AHTR7DRD2PARP1 | |
| SCHEMBL11630735 | 0.83 | HTR1A (0.48) | SIGMAR1HTR1AL3MBTL1HTR7DRD2 | |
| SCHEMBL11633300 | 0.79 | HTR1A (0.50) | SIGMAR1HTR1AHTR7PARP1 | |
| SCHEMBL11632779 | 0.79 | HTR1A (0.50) | SIGMAR1HTR1AHTR7PARP1 | |
| SCHEMBL9869152 | 0.79 | HTR1A (0.55) | SIGMAR1HTR1AHTR7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | claimed |
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | disclosed |