Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867198 | 0.92 | HTR1A (0.53) | SIGMAR1HTR1APARP1 | |
| SCHEMBL9867975 | 0.89 | HTR1A (0.49) | SIGMAR1HTR1ADRD2HTR7PARP1 | |
| Oxalic Acid SCHEMBL9867718 | 0.88 | SIGMAR1 (0.50) | SIGMAR1HTR1ADRD2HTR7PARP1 | |
| SCHEMBL9866903 | 0.86 | SIGMAR1 (0.51) | SIGMAR1HTR1ADRD2HTR7PARP1 | |
| Oxalic Acid SCHEMBL9868486 | 0.85 | SIGMAR1 (0.53) | SIGMAR1HTR1ADRD2HTR7PARP1 | |
| SCHEMBL9867799 | 0.85 | HTR1A (0.51) | SIGMAR1HTR1APARP1 | |
| Oxalic Acid SCHEMBL9868595 | 0.83 | HTR1A (0.49) | SIGMAR1HTR1APARP1 | |
| Oxalic Acid SCHEMBL9867563 | 0.81 | HTR1A (0.51) | SIGMAR1HTR1APARP1DRD3 | |
| Oxalic Acid SCHEMBL9866814 | 0.81 | HTR1A (0.47) | SIGMAR1HTR1APARP1 | |
| Oxalic Acid SCHEMBL9868038 | 0.81 | HTR1A (0.47) | SIGMAR1HTR1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2072158-A | — | — | None | — | — | JP | disclosed |
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | disclosed |
| JP-H0272158-A | ISOINDOLINONE DERIVATIVE, ITS PREPARATION AND DRUG CONTAINING THE SAME | RHONE POULENC SANTE | 1990-03-12 | — | — | JP | disclosed |