Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865994 | 0.86 | CRHBP (0.39) | CRHBPCRHR2TOP1TSHRCFD | |
| SCHEMBL9867553 | 0.76 | CHRM2 (0.41) | CRHBPCRHR2TSHRCFDHTT | |
| SCHEMBL10441976 | 0.76 | CRHBP (0.40) | CRHBPCRHR2TOP1TSHRCFD | |
| SCHEMBL9866936 | 0.74 | TOP1 (0.43) | TOP1TSHRCFDHTTALDH1A1 | |
| SCHEMBL2159876 | 0.73 | CRHBP (0.53) | CRHBPCRHR2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9867128 | 0.73 | ALDH1A1 (0.41) | CRHBPCRHR2TSHRCFDHTT | |
| SCHEMBL10442204 | 0.72 | CRHBP (0.38) | CRHBPCRHR2TOP1TSHRCFD | |
| SCHEMBL4911331 | 0.72 | CRHBP (0.69) | CRHBPCRHR2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9734696 | 0.70 | TOP1 (0.46) | TOP1TSHRCFDHTTALDH1A1 | |
| SCHEMBL9865985 | 0.70 | TOP1 (0.41) | TOP1TSHRHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001121-A | Cephalosporin compounds and pharmaceutical compositions thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4956474-A | PHTHALIMIDOOXY OR AMINOXY COMPOUNDS FOR MAKING CEPHALOSPORINS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0360298-A2 | Intermediate compounds for use in the synthesis of cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0359291-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4904791-A | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4840945-A | ANTIBIOTICS EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0197409-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-15 | — | — | EP | disclosed |
| WO-1986005786-A1 | CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |