Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867553 | 0.87 | CHRM2 (0.41) | ALDH1A1LMNAALOX15CHRM2CHRM1 | |
| SCHEMBL9865994 | 0.75 | CRHBP (0.39) | ALDH1A1TSHRCFDCRHBPCRHR2 | |
| SCHEMBL9866994 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL9868777 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL9866940 | 0.73 | CRHBP (0.41) | ALDH1A1TSHRCFDPTGS1CRHBP | |
| SCHEMBL2417527 | 0.71 | PTGS1 (0.48) | ALDH1A1ALOX15TSHRCFDCCR5 | |
| SCHEMBL10442204 | 0.70 | CRHBP (0.38) | ALDH1A1LMNACYP3A4TSHRCFD | |
| SCHEMBL6221039 | 0.70 | ALOX15 (0.51) | ALDH1A1ALOX15TSHRCFDCCR5 | |
| SCHEMBL9867123 | 0.68 | ALDH1A1 (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10693575 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRCFDCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001121-A | Cephalosporin compounds and pharmaceutical compositions thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0197409-B1 | CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4956474-A | PHTHALIMIDOOXY OR AMINOXY COMPOUNDS FOR MAKING CEPHALOSPORINS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0360298-A2 | Intermediate compounds for use in the synthesis of cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0359291-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4904791-A | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4840945-A | ANTIBIOTICS EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0197409-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-15 | — | — | EP | disclosed |
| WO-1986005786-A1 | CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |