Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866582 | 0.88 | BCHE (0.40) | KAT8MEN1KMT2AARALDH1A1 | |
| SCHEMBL9866386 | 0.85 | MEN1 (0.43) | KAT8MEN1KMT2AARALDH1A1 | |
| SCHEMBL9865807 | 0.81 | NAAA (0.34) | — | |
| SCHEMBL9867527 | 0.80 | TRPV3 (0.44) | KAT8ARALDH1A1HPGDTRPV3 | |
| SCHEMBL9865370 | 0.80 | AR (0.39) | KAT8MEN1KMT2AARALDH1A1 | |
| SCHEMBL9866711 | 0.80 | NPY5R (0.41) | KAT8MEN1KMT2AARALDH1A1 | |
| SCHEMBL9866294 | 0.79 | BCHE (0.41) | KAT8TRPV3PKMBCHE | |
| SCHEMBL10374044 | 0.76 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL9734839 | 0.74 | CA1 (0.50) | KAT8MEN1KMT2AALDH1A1TRPV3 | |
| SCHEMBL2524154 | 0.71 | L3MBTL1 (0.52) | TRPV3PKMLMNAGRM5SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |