Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867797 | 0.85 | MEN1 (0.33) | HTR7 | |
| SCHEMBL9867957 | 0.82 | MEN1 (0.33) | HTR7NFE2L2 | |
| SCHEMBL9866979 | 0.81 | KAT8 (0.38) | — | |
| SCHEMBL9866531 | 0.79 | POLB (0.36) | HTR7NFE2L2 | |
| SCHEMBL10374044 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL9869258 | 0.78 | NFE2L2 (0.33) | NFE2L2 | |
| SCHEMBL9866719 | 0.76 | L3MBTL1 (0.38) | — | |
| SCHEMBL9865651 | 0.75 | HCAR1 (0.33) | NFE2L2 | |
| SCHEMBL9866727 | 0.75 | NFE2L2 (0.34) | NFE2L2 | |
| SCHEMBL10373802 | 0.75 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |