Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967703 | 0.75 | — | — | |
| SCHEMBL21680824 | 0.74 | — | — | |
| SCHEMBL491407 | 0.72 | MAPT (0.38) | MAPTHSD17B10MCL1 | |
| SCHEMBL462879 | 0.72 | — | — | |
| SCHEMBL6895976 | 0.71 | — | — | |
| SCHEMBL16931675 | 0.71 | MAPT (0.37) | MAPTHSD17B10MEN1KMT2AMCL1 | |
| SCHEMBL9867939 | 0.70 | LMNA (0.42) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9867654 | 0.70 | KDM4E (0.42) | KDM4ELMNA | |
| SCHEMBL9866601 | 0.70 | CTSD (0.48) | KDM4ELMNAMAPTKMT2AMCL1 | |
| SCHEMBL22961141 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |