Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014878 | 0.77 | — | — | |
| SCHEMBL9866601 | 0.75 | CTSD (0.48) | KDM4ELMNAALDH1A1GAA | |
| SCHEMBL9867939 | 0.75 | LMNA (0.42) | KDM4ELMNACYP1A2TSHRNFKB1 | |
| SCHEMBL27536224 | 0.73 | KDM4E (0.38) | KDM4ELMNA | |
| SCHEMBL9868852 | 0.71 | EPHX1 (0.50) | KDM4ELMNA | |
| SCHEMBL301095 | 0.71 | — | — | |
| SCHEMBL3281043 | 0.70 | — | — | |
| SCHEMBL9867407 | 0.70 | KDM4E (0.39) | KDM4ELMNA | |
| SCHEMBL2321087 | 0.70 | EPHX1 (0.56) | KDM4ELMNA | |
| SCHEMBL9868278 | 0.70 | ANPEP (0.56) | KDM4ELMNAGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |