Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT5 | Q96KN8 | 7/20 | 0.64 |
| ▸ | PLAAT4 | Q9UL19 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | PLAAT3 | P53816 | 6/20 | 0.60 |
| ▸ | PLAAT2 | Q9NWW9 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22412530 | 0.90 | PLAAT5 (0.75) | PLAAT5PLAAT4TAAR1PLAAT3PLAAT2 | |
| SCHEMBL20673342 | 0.83 | SMN1; SMN2 (0.81) | PLAAT5PLAAT4PLAAT3PLAAT2SMN1; SMN2 | |
| SCHEMBL2298030 | 0.83 | PLAAT5 (0.66) | PLAAT5PLAAT4TAAR1PLAAT3PLAAT2 | |
| SCHEMBL18459626 | 0.83 | PLAAT5 (0.67) | PLAAT5PLAAT4PLAAT3PLAAT2SMN1; SMN2 | |
| SCHEMBL4831685 | 0.82 | PLAAT5 (0.70) | PLAAT5PLAAT4TAAR1PLAAT3PLAAT2 | |
| SCHEMBL20711478 | 0.82 | PLAAT3 (0.59) | PLAAT5PLAAT4GAAPLAAT3PLAAT2 | |
| SCHEMBL6175376 | 0.81 | CYP1A2 (0.70) | PLAAT5PLAAT4PLAAT3PLAAT2SMN1; SMN2 | |
| SCHEMBL881512 | 0.81 | KMT2A (0.61) | LMNAGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15682837 | 0.80 | CES2 (0.51) | PLAAT5PLAAT4LMNAGAAPLAAT3 | |
| SCHEMBL3413251 | 0.80 | KMT2A (0.71) | PLAAT5PLAAT4LMNAPLAAT3PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575060-B | Synthesis of spiro bisboron catalyst and application of spiro bisboron catalyst in hydrogenation reaction | 南开大学 | 2020-11-17 | — | — | CN | claimed |
| EP-3661912-B9 | COMPOUNDS FOR TREATING INFECTIONS | HORITZONTS TECNOLOGICS HUNGARY KORLATOLT FELELOSSEGU TARSASAG (HU) | 2024-02-28 | — | — | EP | disclosed |
| EP-3661912-B1 | COMPOUNDS FOR TREATING INFECTIONS | HORITZONTS TECNOLOGICS HUNGARY KORLATOLT FELELOSSEGU TARSASAG (HU) | 2023-11-22 | — | — | EP | disclosed |
| CN-109575060-B | Synthesis of spiro bisboron catalyst and application of spiro bisboron catalyst in hydrogenation reaction | 南开大学 | 2020-11-17 | — | — | CN | disclosed |
| EP-2914575-B1 | PLASMINOGEN ACTIVATOR-1 INHIBITORS AND METHODS OF USE THEREOF | UNIV MICHIGAN REGENTS (US) | 2020-10-14 | — | — | EP | disclosed |
| US-20170291893-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF | EASTERN MICHIGAN UNIVERSITY | 2017-10-12 | — | — | US | disclosed |
| US-9718760-B2 | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-08-01 | — | — | US | disclosed |
| US-20150315178-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-11-05 | — | — | US | disclosed |
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291893-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF | SERPINE1, PLAT, SERPINC1 | PLAAT5 92/4885PLAAT4 86/4885LMNA 753/4885 |
| US-20150315178-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF | SERPINE1, PLAT, SERPINC1 | PLAAT5 92/4885PLAAT4 86/4885LMNA 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.