SCHEMBL986790

SCHEMBL986790

COC(=O)c1cc(-n2c3ccccc3c3ccccc32)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
NR4A2 P43354 2/20 0.48
PMM2 O15305 1/20 0.47
MPI P34949 1/20 0.47
RAB9A P51151 1/20 0.47
PHOSPHO1 Q8TCT1 1/20 0.47
ALDH1A1 P00352 3/20 0.47
LMNA P02545 1/20 0.47
KDM4E B2RXH2 3/20 0.46
POLB P06746 1/20 0.46
EGFR P00533 1/20 0.46
SRC P12931 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13157837 0.87 POLB (0.57) TSHRNR4A2RAB9AALDH1A1LMNA
SCHEMBL30128111 0.83 KDM4E (0.53) NR4A2PMM2MPIRAB9APHOSPHO1
SCHEMBL29145908 0.83 KDM4E (0.53) NR4A2PMM2MPIRAB9APHOSPHO1
SCHEMBL3844231 0.83 ALDH1A1 (0.54) TSHRNR4A2PMM2MPIRAB9A
SCHEMBL3663983 0.83 PTGER4 (0.46) TSHRNR4A2ALDH1A1LMNAKDM4E
SCHEMBL13767949 0.82 SRC (0.37) TSHRNR4A2PMM2MPIRAB9A
SCHEMBL20252384 0.81 POLB (0.45) TSHRNR4A2ALDH1A1LMNAKDM4E
SCHEMBL133459 0.80 KDM4E (0.54) ALDH1A1LMNAKDM4EPOLBMAPT
SCHEMBL15890166 0.80 POLB (0.46) ALDH1A1LMNAKDM4EPOLBEGFR
SCHEMBL10000337 0.80 HPGD (0.41) ALDH1A1LMNAKDM4EPOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101952251-B Carbazole-based hole transport and /or electron blocking materials and /or host polymer materials GEORGIA TECH RES INST 2014-11-26 CN disclosed
WO-2014011477-A1 HIGH GLASS TRANSITION TEMPERATURE \"MEDIUM-SIZED\" AMBIPOLAR HOST MATERIALS GEORGIA TECH RESEARCH CORPORATION (US) 2014-01-16 WO disclosed
WO-2014011491-A1 CARBAZOLE SUBSTITUTED TRIAZOLE, TRIAZINE, AND TETRAZINE AMBIPOLAR HOST MATERIALS AND DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2014-01-16 WO disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
WO-2012088316-A1 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS GEORGIA TECH RESEARCH CORPORATION (US) 2012-06-28 WO disclosed
WO-2012088316-A1 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS GEORGIA TECH RESEARCH CORPORATION (US) 2012-06-28 WO disclosed
WO-2011000873-A1 PHOSPHORESCENT PLATINUM COMPLEXES, THEIR MONOMERS AND COPOLYMERS, AND USES IN ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2011-01-06 WO disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
EP-2234969-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS Georgia Tech Research Corporation (US) 2010-10-06 EP disclosed
WO-2009080799-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials OCIAD1, HPD, OXA1L TSHR 4837/4885NR4A2 1256/4885PMM2 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.