SCHEMBL10000337

SCHEMBL10000337

COC(=O)c1cc(CO)cc(OCc2cc(-n3c4ccccc4c4ccccc43)cc(-n3c4ccccc4c4ccccc43)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.41
LMNA P02545 1/20 0.41
MRGPRX4 Q96LA9 3/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
PRSS1 P07477 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
ALOX15 P16050 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPK8 P45983 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000341 0.91 LMNA (0.40) HPGDLMNAMRGPRX4MEN1KMT2A
SCHEMBL13754822 0.85 F2 (0.43) MEN1KMT2ASMN1; SMN2F2F10
SCHEMBL3132629 0.80 LMNA (0.62) HPGDLMNAMRGPRX4MEN1KMT2A
SCHEMBL13815331 0.80 F2 (0.39) HPGDLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL986790 0.80 TSHR (0.48) HPGDLMNAMEN1KMT2AF2
SCHEMBL4151119 0.75 PSEN1 (0.47) HPGDLMNASMN1; SMN2KDM4EMAPT
SCHEMBL3664509 0.74 KDM4E (0.57) HPGDKMT2AF2F10PRSS1
SCHEMBL13754824 0.74 CYP1A2 (0.47) LMNAMEN1KMT2AF2F10
SCHEMBL2177575 0.74 MAOB (0.51) HPGDLMNAMRGPRX4KDM4EMAPT
SCHEMBL13754821 0.73 F2 (0.39) MEN1KMT2AF2F10PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124767-B2 Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US disclosed
US-8124767-B2 Luminescence biotin-transition metal complex conjugate, and method of amplifying signal using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US disclosed
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-08-20 US disclosed
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209048-A1 Luminescence Biotin-Transition Metal Complex Conjugate, and Method of Amplifying Signal Using the Same BTD, HLCS, BPGM HPGD 1708/4885LMNA 590/4885MRGPRX4 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.