SCHEMBL3663983

SCHEMBL3663983

COC(=O)c1cc(-n2c3ccccc3c3ccccc32)nc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.46
ELANE P08246 3/20 0.46
F2 P00734 2/20 0.46
PLAU P00749 2/20 0.46
TSHR P16473 1/20 0.44
NR4A2 P43354 1/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 1/20 0.44
KDM4E B2RXH2 2/20 0.44
EGFR P00533 1/20 0.43
SRC P12931 1/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CB P42338 1/20 0.43
KMT2A Q03164 2/20 0.43
THRB P10828 1/20 0.43
KIF11 P52732 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3666739 0.89 PTGER4 (0.43) PTGER4ELANEF2PLAUPOLB
SCHEMBL20252383 0.83 POLB (0.41) PTGER4ELANEF2PLAUTSHR
SCHEMBL986790 0.83 TSHR (0.48) ELANEF2PLAUTSHRNR4A2
SCHEMBL24930834 0.81 KDM4E (0.49) TSHRPOLBALDH1A1LMNAKDM4E
SCHEMBL13063211 0.80 PTGER4 (0.34) PTGER4ELANEF2PLAUTSHR
SCHEMBL13018678 0.80 KIF11 (0.45) F2ALDH1A1LMNAKDM4EEGFR
SCHEMBL18617350 0.78 ALDH1A1 (0.49) TSHRPOLBALDH1A1LMNAKDM4E
SCHEMBL13011184 0.77 POLB (0.49) PTGER4TSHRPOLBALDH1A1LMNA
SCHEMBL13157837 0.76 POLB (0.57) TSHRNR4A2POLBALDH1A1LMNA
SCHEMBL30128111 0.74 KDM4E (0.53) PTGER4NR4A2POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
EP-2234969-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS Georgia Tech Research Corporation (US) 2010-10-06 EP disclosed
WO-2009080799-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed
WO-2009080799-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials OCIAD1, HPD, OXA1L PTGER4 1209/4885ELANE 3169/4885F2 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.