SCHEMBL9868048

SCHEMBL9868048

Cc1ccc(Oc2ccc(C)cc2C=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.53
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 2/20 0.42
AR P10275 1/20 0.41
SRC P12931 1/20 0.41
HTT P42858 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
ERN1 O75460 2/20 0.40
TEAD4 Q15561 1/20 0.39
TTR P02766 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5321372 0.90 NPSR1 (0.47) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL21129706 0.89 LMNA (0.62) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL22809589 0.82 SLC6A4 (0.56) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL1200720 0.81 LMNA (0.74) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL6923805 0.81 TBXA2R (0.49) ALDH1A1LMNAGAAKMT2AHTT
SCHEMBL22809762 0.81 ERN1 (0.46) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL25642257 0.81 TUBB1 (0.51) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL19563692 0.79 NPSR1 (0.44) NPSR1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL419596 0.79 ALDH1A1 (0.57) ALDH1A1LMNACYP1A2CYP2C9CYP2C19
SCHEMBL11798797 0.77 ALDH1A1 (0.47) NPSR1ALDH1A1LMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030670-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1991-07-09 US claimed
US-4780494-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1988-10-25 US claimed
US-5030670-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1991-07-09 US disclosed
EP-0306791-A1 Self-levelling mortar mixture BAYER AG (DE) 1989-03-15 EP disclosed
US-4780494-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1988-10-25 US disclosed