Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868404 | 0.96 | HTR3A (0.41) | HTR3ADRD2 | |
| Fumaric Acid SCHEMBL9866836 | 0.91 | HTR3A (0.38) | HTR3ADRD2 | |
| SCHEMBL9866954 | 0.87 | — | — | |
| SCHEMBL9868954 | 0.82 | — | — | |
| SCHEMBL9868466 | 0.82 | DRD2 (0.31) | DRD2 | |
| SCHEMBL9866732 | 0.72 | SMYD3 (0.30) | — | |
| SCHEMBL9868274 | 0.70 | DRD2 (0.51) | DRD2 | |
| SCHEMBL9822989 | 0.68 | HTR3A (0.42) | HTR3A | |
| SCHEMBL10721843 | 0.68 | DRD3 (0.49) | DRD2 | |
| Hydrochloric Acid SCHEMBL9406901 | 0.67 | DRD2 (0.61) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | claimed |