SCHEMBL9868466

SCHEMBL9868466

CNS(=O)(=O)c1cc2c(c(C(=O)NC(C)C3CCCN3C3=CCCCC3)c1)OCCC2

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9868954 0.91
SCHEMBL9868404 0.86 HTR3A (0.41) DRD2
Fumaric Acid SCHEMBL9866836 0.82 HTR3A (0.38) DRD2
SCHEMBL9868070 0.82 HTR3A (0.46) DRD2
SCHEMBL9866732 0.76 SMYD3 (0.30)
SCHEMBL9822852 0.74 DRD2 (0.46) DRD2
SCHEMBL9868293 0.73 DRD2 (0.33) DRD2
SCHEMBL9822842 0.73 ALDH1A1 (0.31)
SCHEMBL9866954 0.73
SCHEMBL9866511 0.72 DRD2 (0.32) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006570-A Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics LABORATOIRES DELAGRANGE (FR) 1991-04-09 US claimed