Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865358 | 0.88 | MLNR (0.64) | MLNRADRB2CHRM1DRD2ADRA2B | |
| SCHEMBL9867256 | 0.88 | MLNR (0.84) | MLNRADRB2CHRM1DRD2ADRA2B | |
| Hydrochloric Acid SCHEMBL11544323 | 0.87 | HTR4 (0.64) | HTR4ACHE | |
| SCHEMBL9866832 | 0.87 | DRD2 (0.54) | MLNRADRB2CHRM1DRD2ADRA2B | |
| SCHEMBL9866959 | 0.86 | DRD4 (0.56) | MLNRADRB2CHRM1DRD2ADRA2B | |
| Denipride SCHEMBL2108137 | 0.86 | DRD2 (0.57) | MLNRADRB2CHRM1DRD2ADRA2B | |
| SCHEMBL11545317 | 0.85 | HTR4 (0.78) | HTR4 | |
| SCHEMBL11548165 | 0.85 | HTR4 (0.77) | HTR4ACHE | |
| Hydrochloric Acid SCHEMBL11544697 | 0.84 | HTR4 (0.77) | HTR4 | |
| Hydrochloric Acid SCHEMBL11544953 | 0.84 | HTR4 (0.77) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026858-A | Used for treating nausea, vomating, gastrointestinal disorders and centarl nervous system | WALTON S.A. (ES) | 1991-06-25 | — | — | US | disclosed |