Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523202 | 0.88 | TBXAS1 (0.53) | TBXAS1CYP19A1 | |
| SCHEMBL9523831 | 0.85 | TBXAS1 (0.52) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL9525196 | 0.84 | LMNA (0.48) | ALDH1A1TBXAS1CYP19A1 | |
| Hydrochloric Acid SCHEMBL9523846 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TBXAS1CYP19A1 | |
| Hydrochloric Acid SCHEMBL9524018 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TBXAS1CYP19A1 | |
| SCHEMBL9527175 | 0.80 | CYP19A1 (0.47) | ALDH1A1TBXAS1CYP19A1 | |
| SCHEMBL10851510 | 0.77 | TBXAS1 (0.67) | ALDH1A1ABL1RIN1TBXAS1CYP19A1 | |
| SCHEMBL9527191 | 0.76 | CYP19A1 (0.52) | ALDH1A1TBXAS1CYP19A1 | |
| SCHEMBL11477428 | 0.75 | TBXAS1 (0.67) | ALDH1A1ABL1RIN1TBXAS1CYP19A1 | |
| SCHEMBL29239308 | 0.74 | TBXAS1 (0.62) | ALDH1A1ABL1RIN1TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039677-A | Estrogen inhibitor | JANSSEN PHARMACEUTICA N.V. (CA) | 1991-08-13 | — | — | US | disclosed |
| US-4943574-A | AROMATASE INHIBITORS, ESTROGEN DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |