Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866511 | 0.92 | DRD2 (0.32) | DRD2 | |
| SCHEMBL9868311 | 0.84 | DRD2 (0.33) | DRD2ADRA2BADRA2CSLC6A4DRD3 | |
| SCHEMBL9868954 | 0.83 | — | — | |
| SCHEMBL9868466 | 0.73 | DRD2 (0.31) | DRD2 | |
| SCHEMBL9822959 | 0.72 | DRD2 (0.30) | DRD2 | |
| SCHEMBL9822683 | 0.72 | DRD2 (0.51) | DRD2ADRA2BADRA2CSLC6A4DRD3 | |
| SCHEMBL9822666 | 0.72 | KEAP1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL9868759 | 0.71 | BACE1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL9868756 | 0.71 | DRD2 (0.51) | DRD2ADRA2BADRA2CSLC6A4DRD3 | |
| SCHEMBL10563146 | 0.71 | DRD2 (0.60) | DRD2ADRA2BADRA2CSLC6A4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | claimed |