Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 11/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 11/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.49 |
| ▸ | GABRP | O00591 | 6/20 | 0.49 |
| ▸ | GABRD | O14764 | 6/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.49 |
| ▸ | GABRE | P78334 | 6/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513741 | 0.83 | CA12 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9868685 | 0.77 | BRD4 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9869982 | 0.75 | ADORA3 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29329014 | 0.74 | RAB9A (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10465784 | 0.72 | TSHR (0.47) | HPGDALDH1A1MAPTCA12CA1 | |
| SCHEMBL9434187 | 0.71 | BRD4 (0.49) | HPGDALDH1A1MAPTNR1H2NR1H3 | |
| SCHEMBL31623843 | 0.70 | GABRA1 (0.73) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5846548 | 0.70 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30968739 | 0.70 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9586331 | 0.69 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997947-A | Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |