Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NMT2 | O60551 | 6/20 | 0.49 |
| ▸ | NMT1 | P30419 | 6/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608031 | 0.86 | RAB9A (0.65) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL3614948 | 0.83 | RAB9A (0.62) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL4629109 | 0.83 | RAB9A (0.65) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL10738691 | 0.83 | RAB9A (0.74) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL9869198 | 0.81 | EDNRA (0.47) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL6871537 | 0.81 | RAB9A (0.62) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL10743101 | 0.81 | RAB9A (0.62) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL3610943 | 0.81 | RAB9A (0.62) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL9866325 | 0.80 | RAB9A (0.58) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL9867487 | 0.80 | RAB9A (0.48) | RAB9ANPC1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006549-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0399773-A1 | Novel 7-aroyl-4-hydroxy-3-methyl benzolfurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |