Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868567 | 0.81 | RAB9A (0.59) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL10743811 | 0.81 | EDNRA (0.49) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL27593840 | 0.81 | MCL1 (0.54) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL27593873 | 0.78 | EDNRA (0.49) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL9868498 | 0.77 | GLRA3 (0.49) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL9868477 | 0.77 | MCL1 (0.43) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL5789823 | 0.76 | EDNRA (0.48) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL9867950 | 0.71 | NPC1 (0.38) | EDNRAMCL1MEN1KMT2AKDM4E | |
| SCHEMBL3611742 | 0.70 | MAPT (0.65) | EDNRAMCL1GPR35MEN1KMT2A | |
| SCHEMBL3612485 | 0.68 | EDNRA (0.66) | EDNRAMCL1GPR35MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006549-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |