SCHEMBL9868670

SCHEMBL9868670

CCN1CCCC1CNC(=O)c1cccc2c1OCCC2

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL9867365 0.94 DRD2 (0.52) DRD2
Fumaric Acid SCHEMBL9867378 0.94 DRD2 (0.52) DRD2
SCHEMBL11265595 0.86 DRD2 (0.59) DRD2
Water SCHEMBL11269883 0.85 DRD2 (0.58) DRD2
SCHEMBL11356294 0.85 HTR4 (0.61) DRD2
Hydrochloric Acid SCHEMBL11265728 0.84 HTR4 (0.60) DRD2
Phosphoric Acid SCHEMBL11259891 0.84 DRD2 (0.56) DRD2
SCHEMBL9484536 0.82 DRD2 (0.62) DRD2
SCHEMBL11257248 0.81 DRD2 (0.60) DRD2
SCHEMBL10810631 0.81 CA2 (0.60) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1062144-A The preparation method of benzodihydropyran carboxamide derivatives DELAGRANGE LAB (FR) 1992-06-24 CN disclosed
US-5006570-A Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics LABORATOIRES DELAGRANGE (FR) 1991-04-09 US disclosed
CN-87100978-A Dihydrobenzofuran-and chroman-carboxamide derivatives, processes for their preparation and their use as neuroleptics 1987-09-16 CN disclosed