Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667515 | 0.91 | ESR1 (0.53) | ALDH1A1MAPTPOLBLMNAMAPK1 | |
| SCHEMBL9502178 | 0.88 | TSHR (0.56) | MAPTLMNATSHRRAB9ANPC1 | |
| SCHEMBL3817682 | 0.88 | TSHR (0.52) | ALDH1A1MAPTPOLBLMNAMAPK1 | |
| SCHEMBL9488693 | 0.87 | GAA (0.50) | ALDH1A1MAPTPOLBLMNAMAPK1 | |
| SCHEMBL9500186 | 0.87 | TSHR (0.58) | LMNATSHRNPC1PLA2G4BSMN1; SMN2 | |
| SCHEMBL17577041 | 0.87 | RARB (0.54) | MAPTTSHRRAB9APLA2G4B | |
| SCHEMBL18464124 | 0.85 | PDCD1 (0.61) | ALDH1A1MAPTPOLBLMNAMAPK1 | |
| SCHEMBL1129618 | 0.85 | ESR1 (0.64) | ALDH1A1MAPTPOLBLMNAMAPK1 | |
| SCHEMBL21396286 | 0.85 | PDCD1 (0.61) | ALDH1A1MAPTPOLBLMNAMAPK1 | |
| SCHEMBL9499271 | 0.85 | NPSR1 (0.53) | ALDH1A1MAPTPOLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |