Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667515 | 0.96 | ESR1 (0.53) | TSHRTP53ALDH1A1LMNAESR1 | |
| SCHEMBL6669351 | 0.92 | MAPT (0.46) | TSHRTP53ALDH1A1LMNAESR1 | |
| SCHEMBL1129618 | 0.90 | ESR1 (0.64) | TSHRTP53ALDH1A1LMNAESR1 | |
| SCHEMBL21396286 | 0.90 | PDCD1 (0.61) | ALDH1A1LMNAESR1ESR2POLB | |
| SCHEMBL9499271 | 0.90 | NPSR1 (0.53) | ALDH1A1LMNAESR1ESR2POLB | |
| SCHEMBL18464124 | 0.90 | PDCD1 (0.61) | ALDH1A1LMNAESR1ESR2POLB | |
| SCHEMBL9500077 | 0.90 | ALDH1A1 (0.55) | TSHRTP53ALDH1A1LMNAESR1 | |
| SCHEMBL9499131 | 0.89 | UTS2R (0.60) | ALDH1A1ESR1ESR2SLC6A4SLC6A3 | |
| SCHEMBL9498568 | 0.89 | ALDH1A1 (0.49) | ALDH1A1LMNAESR1ESR2POLB | |
| SCHEMBL9500237 | 0.89 | NPC1 (0.48) | ALDH1A1LMNAESR1ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107014914-A | A kind of method of formula isomers and nitrobenzoyl phenyl propane compounds while Analyze ＆ separate FCE-20124 is revived | 重庆医药高等专科学校 | 2017-08-04 | — | — | CN | claimed |
| WO-2008014505-A2 | BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-20240374492-A1 | A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION | ISP INVESTMENTS LLC (US) | 2024-11-14 | — | — | US | disclosed |
| CN-113811287-B | Low VOC multi-functional additives for improving waterborne polymer film properties | 朗盛公司 | 2023-11-17 | — | — | CN | disclosed |
| US-20220041871-A1 | LOW VOC MULTIFUNCTIONAL ADDITIVES TO IMPROVE WATERBORNE POLYMER FILM PROPERTIES | EMERALD KALAMA CHEMICAL, LLC (US) | 2022-02-10 | — | — | US | disclosed |
| EP-3946249-A1 | LOW VOC MULTIFUNCTIONAL ADDITIVES TO IMPROVE WATERBORNE POLYMER FILM PROPERTIES | Emerald Kalama Chemical, LLC (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113069382-A | Skin-activating cream | 李树玲 | 2021-07-06 | — | — | CN | disclosed |
| WO-2020206296-A1 | LOW VOC MULTIFUNCTIONAL ADDITIVES TO IMPROVE WATERBORNE POLYMER FILM PROPERTIES | EMERALD KALAMA CHEMICAL, LLC (US) | 2020-10-08 | — | — | WO | disclosed |
| CN-108431019-A | DOSING REGIMENS | 阿佩利斯制药有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-107014914-A | A kind of method of formula isomers and nitrobenzoyl phenyl propane compounds while Analyze ＆ separate FCE-20124 is revived | 重庆医药高等专科学校 | 2017-08-04 | — | — | CN | disclosed |
| CN-102639494-B | Sulphones and preparation and application thereof | 扎夫根公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-1802290-A4 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTIMENTS INC (US) | 2009-08-19 | — | — | EP | disclosed |
| US-7361668-B2 | Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors | UCB, S.A. (BE) | 2008-04-22 | — | — | US | disclosed |
| WO-2008014505-A2 | BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| EP-1802290-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP Investiments Inc. (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006041506-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20050152858-A1 | Solubilizing agents for active or functional organic compounds | ISP INVESTMENTS INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050152858-A1 | Solubilizing agents for active or functional organic compounds | MITF, TYR, MMS19 | TSHR 4233/4885TP53 167/4885ALDH1A1 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.