SCHEMBL9869188

SCHEMBL9869188

CNCc1ccc(N)c2c1SCCC2=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9404990 0.78 THRB (0.39) LMNAMAPT
SCHEMBL9404777 0.75 LMNA (0.36) LMNAMAPT
SCHEMBL9404799 0.72 THRB (0.31) LMNAMAPT
SCHEMBL7661312 0.71 HDAC1 (0.38) MAPT
SCHEMBL9404931 0.65 MAOA (0.33) MAPT
SCHEMBL7653076 0.65 HDAC1 (0.38) MAPT
SCHEMBL7840446 0.64 BRD4 (0.34)
SCHEMBL26606804 0.63 KDM4E (0.30)
SCHEMBL9866815 0.62 L3MBTL1 (0.32)
SCHEMBL9404887 0.62 VHL (0.39) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5061795-A ANTITUMOR AGENTS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1991-10-29 US disclosed