Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.34 |
| ▸ | GLRB | P48167 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737005 | 0.84 | MCL1 (0.50) | MCL1GPR35HPGDKDM4EL3MBTL1 | |
| SCHEMBL9866325 | 0.82 | RAB9A (0.58) | HPGDKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL9868498 | 0.79 | GLRA3 (0.49) | MCL1GPR35HPGDKDM4EL3MBTL1 | |
| SCHEMBL9869198 | 0.77 | EDNRA (0.47) | MCL1GPR35HPGDKDM4EL3MBTL1 | |
| SCHEMBL9867950 | 0.70 | NPC1 (0.38) | MCL1HPGDKDM4EL3MBTL1EDNRA | |
| SCHEMBL3611742 | 0.69 | MAPT (0.65) | MCL1GPR35HPGDKDM4EEDNRA | |
| SCHEMBL17843607 | 0.68 | MCL1 (0.61) | MCL1GPR35HPGDKDM4EL3MBTL1 | |
| SCHEMBL9868574 | 0.68 | MCL1 (0.39) | MCL1HPGDKDM4EL3MBTL1MEN1 | |
| SCHEMBL2269577 | 0.66 | ALDH1A1 (0.37) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10743811 | 0.64 | EDNRA (0.49) | MCL1GPR35HPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006549-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0399773-A1 | Novel 7-aroyl-4-hydroxy-3-methyl benzolfurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |