Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.41 |
| ▸ | CCKAR | P32238 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087130 | 0.73 | KCNH2 (0.49) | CYP2C9MAPK1GAAALDH1A1HTT | |
| SCHEMBL9726866 | 0.70 | LRRK2 (0.41) | MAPK1EGFRGABRPGABRDGABRA1 | |
| SCHEMBL8716727 | 0.68 | CCKAR (0.31) | CCKBRCCKAR | |
| SCHEMBL6920408 | 0.65 | CHEK1 (0.36) | EGFRSRCGAAHDAC4HDAC7 | |
| SCHEMBL1868702 | 0.64 | SETDB1 (0.40) | CCKBR | |
| Hydrochloric Acid SCHEMBL7208149 | 0.64 | CHEK1 (0.36) | EGFRSRCGAAHDAC4HDAC7 | |
| SCHEMBL8977555 | 0.62 | CCKBR (0.81) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL5718666 | 0.61 | PTPN1 (0.71) | POLBHTTMEN1KMT2A | |
| SCHEMBL7103601 | 0.61 | MEN1 (0.68) | POLBMAPK1MEN1KMT2A | |
| SCHEMBL9704603 | 0.59 | OPRK1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994258-A | Radiolabeled cholecystokinin-A antagonists bind to receptors | MERCK & CO., INC. (US) | 1991-02-19 | — | — | US | disclosed |