Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869447 | 0.88 | PDK1 (0.49) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL2972082 | 0.80 | SLC9A1 (0.60) | LMNASLC9A1CXCR2MAPTKMT2A | |
| SCHEMBL10421023 | 0.76 | AR (0.52) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL10420241 | 0.76 | MAPT (0.57) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL9869459 | 0.75 | LMNA (0.41) | LMNASLC9A1CXCR2MAPTMEN1 | |
| SCHEMBL10579855 | 0.75 | CXCR2 (0.56) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL27941949 | 0.75 | SLC9A1 (0.60) | LMNASLC9A1CXCR2MAPTKMT2A | |
| SCHEMBL1455497 | 0.74 | POLB (0.60) | LMNACXCR2MAPTMEN1KMT2A | |
| SCHEMBL21723290 | 0.74 | LMNA (0.45) | LMNASLC9A1CXCR2MAPTMEN1 | |
| SCHEMBL10744542 | 0.73 | PDK1 (0.48) | PDK1PDK2PDK3PDK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| US-4992471-A | Fluorinated carboxanilide | LILLY INDUSTRIES LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0238351-A2 | Molluscicides | LILLY INDUSTRIES LIMITED (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0197756-A2 | Alkanoyl anilides | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197451-A2 | Energy submetering system | HONEYWELL INC. (US) | 1986-10-15 | — | — | EP | disclosed |