Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | C1R | P00736 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KLK3 | P07288 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867803 | 0.89 | MAPT (0.56) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL2252128 | 0.84 | MAPT (0.68) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL28335514 | 0.76 | RAB9A (0.69) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL9868318 | 0.76 | F7 (0.62) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL9868146 | 0.76 | NPC1 (0.55) | MAPTKMT2AMEN1C1RALDH1A1 | |
| SCHEMBL220140 | 0.76 | L3MBTL1 (0.50) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL221808 | 0.75 | MMP2 (0.68) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL221529 | 0.75 | CYP2A6 (0.51) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL3043863 | 0.75 | NPC1 (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL3051786 | 0.75 | MMP2 (0.61) | MAPTKMT2AMEN1F2C1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |