Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218700 | 0.93 | HTR2B (0.65) | HTR2BPOLBPKMMAPTHSD17B10 | |
| SCHEMBL14218701 | 0.92 | POLB (0.62) | HTR2BPOLBPKMKDM4E | |
| SCHEMBL666433 | 0.89 | PARP1 (0.60) | HTR2BPOLBPKMMPOMAPT | |
| SCHEMBL9870915 | 0.87 | HTR2B (0.56) | HTR2BPOLBPKMMPOMAPT | |
| SCHEMBL664921 | 0.85 | HTR2B (0.57) | HTR2BPOLBPKMCHRNA7KDM4E | |
| SCHEMBL9869744 | 0.83 | PKM (0.56) | HTR2BPOLBPKMKDM4EKMT2A | |
| SCHEMBL30365989 | 0.83 | PKM (0.56) | HTR2BPOLBPKMKDM4EKMT2A | |
| SCHEMBL738976 | 0.82 | POLB (0.63) | HTR2BPOLBPKMKDM4E | |
| SCHEMBL662101 | 0.82 | PARP1 (0.64) | HTR2BCHRNA7 | |
| SCHEMBL6883705 | 0.80 | PKM (0.62) | HTR2BPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063228-A | 4-(substitutedaminoethyl)-3,4-dihydro-2-alkylpyrimido[1,6-a]benzimidazol-1(2H)-ones as antiarrhythmic agents | A. H. ROBBINS COMPANY, INCORPORATED (US) | 1991-11-05 | — | — | US | disclosed |