Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311566 | 0.86 | ALDH2 (0.52) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9869238 | 0.76 | PLK4 (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL8028 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL31264756 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL6290885 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL6542422 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL5846515 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL5846511 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL5854324 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11755252 | 0.73 | MAP4K4 (0.36) | ALDH1A1KDM4ESMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034531-A | Viricides | SCHERING CORPORATION (US) | 1991-07-23 | — | — | US | claimed |
| US-5034531-A | Viricides | SCHERING CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |