Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | FES | P07332 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.47 |
| ▸ | FER | P16591 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869472 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL27839334 | 0.75 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL19180558 | 0.74 | IDO1 (0.40) | AURKAJAK2PRKD3MAP4K4IGF1R | |
| SCHEMBL28792827 | 0.74 | PTPN1 (0.54) | CSNK2A1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19196720 | 0.74 | IDO1 (0.37) | ALDH1A1POLBKMT2AGSK3BIDO1 | |
| SCHEMBL20240784 | 0.70 | GABRP (0.58) | NTRK2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27924239 | 0.67 | ALOX15 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL8028 | 0.66 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL31264756 | 0.66 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL6290885 | 0.66 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034531-A | Viricides | SCHERING CORPORATION (US) | 1991-07-23 | — | — | US | claimed |
| US-5034531-A | Viricides | SCHERING CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |