Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920062 | 0.81 | EGLN2 (0.68) | EGLN2NPC1DPP4BACE1SCN9A | |
| SCHEMBL9869687 | 0.74 | BACE1 (0.68) | EGLN2KDM4EBACE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3599775 | 0.68 | EGLN2 (0.51) | EGLN2NPC1DPP4KDM4EMEN1 | |
| SCHEMBL9869845 | 0.67 | EGLN2 (0.50) | EGLN2NPC1KDM4EKMT2ABACE1 | |
| SCHEMBL3036429 | 0.67 | EGLN2 (0.49) | EGLN2DPP4KDM4EBACE1SMN1; SMN2 | |
| SCHEMBL3604219 | 0.66 | EGLN2 (0.49) | EGLN2NPC1DPP4KDM4EMEN1 | |
| Benzene SCHEMBL27840008 | 0.66 | ALDH1A1 (0.60) | EGLN2NPC1KDM4EHSD11B1SCN9A | |
| SCHEMBL29624840 | 0.65 | AHR (0.64) | KDM4EHSD11B1MAPTRAB9AMGAM | |
| SCHEMBL464507 | 0.65 | AHR (0.64) | KDM4EHSD11B1MAPTRAB9AMGAM | |
| SCHEMBL11009860 | 0.65 | BACE1 (0.62) | EGLN2NPC1BACE1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | claimed |
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | disclosed |