Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874547 | 1.00 | TSHR (0.41) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9870673 | 1.00 | TSHR (0.41) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9870715 | 0.96 | TRPA1 (0.40) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9870549 | 0.92 | ALDH1A1 (0.36) | TSHRALDH1A1LMNACYP3A4TRPA1 | |
| SCHEMBL9871151 | 0.91 | TSHR (0.42) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9871350 | 0.91 | TRPA1 (0.40) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9870411 | 0.89 | CA12 (0.36) | TSHRALDH1A1LMNATP53KDM4E | |
| SCHEMBL9870495 | 0.89 | TRPA1 (0.38) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9869831 | 0.87 | TRPA1 (0.40) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9873316 | 0.85 | MAOA (0.35) | TSHRALDH1A1MAPK1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026492-A | Synergistic; improved wear resistance in internal combustion engines | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1991-06-25 | — | — | US | disclosed |