Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871151 | 0.96 | TSHR (0.42) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9871350 | 0.92 | TRPA1 (0.40) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9870715 | 0.91 | TRPA1 (0.40) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9870495 | 0.88 | TRPA1 (0.38) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9874547 | 0.87 | TSHR (0.41) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9870673 | 0.87 | TSHR (0.41) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9869691 | 0.87 | TSHR (0.41) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9870549 | 0.84 | ALDH1A1 (0.36) | TRPA1TSHRCYP3A4ALDH1A1LMNA | |
| SCHEMBL9869676 | 0.83 | TRPA1 (0.39) | TRPA1TSHRL3MBTL1TDP1CYP3A4 | |
| SCHEMBL9870836 | 0.81 | MAOA (0.39) | TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026492-A | Synergistic; improved wear resistance in internal combustion engines | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1991-06-25 | — | — | US | disclosed |