Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869056 | 0.82 | CA12 (0.46) | TSHRL3MBTL1CYP1A2ALDH1A1MAOB | |
| SCHEMBL9869213 | 0.82 | CA12 (0.46) | TSHRCYP1A2ALDH1A1GAAMAOB | |
| SCHEMBL9308690 | 0.80 | TSHR (0.50) | TSHRMEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL9869424 | 0.77 | KCNH2 (0.54) | TSHRSMN1; SMN2CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL9784691 | 0.75 | KDM4E (0.55) | TSHRSMN1; SMN2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9308330 | 0.74 | TSHR (0.53) | TSHRMEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL14021543 | 0.72 | GPBAR1 (0.70) | CYSLTR2CYSLTR1GPBAR1 | |
| SCHEMBL6306356 | 0.71 | TSHR (0.50) | TSHRMEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL9900502 | 0.71 | HPGDS (0.58) | TSHRMAPK10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28619313 | 0.71 | TSHR (0.50) | TSHRMAPK10SMN1; SMN2MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997947-A | Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |