Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9866623 | 0.99 | — | — | |
| SCHEMBL9866772 | 0.91 | HTR4 (0.30) | HTR4HTR1AADRA2CACHEPTGS1 | |
| SCHEMBL9868594 | 0.84 | BACE1 (0.30) | — | |
| SCHEMBL10561655 | 0.77 | DRD2 (0.42) | HTR4ADRA2CACHEHTR3AKCNH2 | |
| SCHEMBL9822959 | 0.77 | DRD2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9868759 | 0.77 | BACE1 (0.31) | — | |
| SCHEMBL9868848 | 0.76 | BACE1 (0.33) | — | |
| SCHEMBL9823201 | 0.76 | — | — | |
| SCHEMBL9867269 | 0.73 | APP (0.34) | HTR4HTR3A | |
| SCHEMBL9869736 | 0.73 | DRD2 (0.45) | ADRA2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |