Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793634 | 0.83 | FDFT1 (0.42) | L3MBTL1KDM4ECA12CA1CA2 | |
| SCHEMBL7784734 | 0.82 | KMT2A (0.45) | KDM4EMAPTPOLBFDFT1LMNA | |
| SCHEMBL8410675 | 0.76 | FFAR1 (0.46) | KDM4EPOLBMEN1KMT2A | |
| SCHEMBL5366533 | 0.75 | FDPS (0.59) | MAPTPOLBLMNAALDH1A1 | |
| SCHEMBL7794868 | 0.75 | FDFT1 (0.66) | CA12CA1CA2CA9KCNQ3 | |
| SCHEMBL7794298 | 0.74 | FDPS (0.60) | L3MBTL1KDM4EMAPTFDFT1LMNA | |
| SCHEMBL7793582 | 0.74 | KDM4E (0.43) | L3MBTL1KDM4ECA12CA1CA2 | |
| SCHEMBL5363659 | 0.74 | RAB9A (0.49) | L3MBTL1KDM4EMAPTPOLBLMNA | |
| SCHEMBL31165568 | 0.72 | DGAT1 (0.42) | KDM4EKCNQ3KCNQ2MAPTPOLB | |
| SCHEMBL7784779 | 0.70 | CRHR1 (0.43) | L3MBTL1MAPTPOLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | claimed |
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | disclosed |
| US-6083938-A | TREATING BONE DISEASES SELECTED FROM THE GROUP CONSISTING OF OSTEOLYTIC BONE DISEASES DUE TO MALIGNANCY, PAGET'S DISEASE AND PRIMARY AND SECONDARY OSTEOPOROSIS | LEIRAS OY (FI) | 2000-07-04 | — | — | US | disclosed |
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | disclosed |