Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220779 | 0.84 | TDP1 (0.46) | TDP1GPR35TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7321325 | 0.81 | ALDH1A1 (0.45) | TDP1TSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL8011477 | 0.81 | ALDH1A1 (0.43) | TDP1GPR35TSHRHSD17B10L3MBTL1 | |
| SCHEMBL8016292 | 0.77 | TDP1 (0.40) | TDP1GPR35TSHRHSD17B10L3MBTL1 | |
| SCHEMBL9536173 | 0.75 | KMT2A (0.47) | TDP1GPR35L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9771589 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8374 | 0.73 | TDP1 (0.54) | TDP1GPR35TSHRHSD17B10L3MBTL1 | |
| SCHEMBL41322 | 0.73 | GPR35 (0.54) | TDP1GPR35TSHRHSD17B10L3MBTL1 | |
| SCHEMBL3063032 | 0.71 | KDM4E (0.35) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL33832 | 0.71 | TDP1 (0.46) | TDP1GPR35TSHRHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071468-A | Cereal selectivity | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-12-10 | — | — | US | disclosed |
| EP-0375076-A1 | Heterocyclic herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-27 | — | — | EP | disclosed |