Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828554 | 0.83 | TDP1 (0.50) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL2766321 | 0.79 | TDP1 (0.34) | TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL456245 | 0.79 | TDP1 (0.44) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL33832 | 0.77 | TDP1 (0.46) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL7136437 | 0.77 | TDP1 (0.46) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL41322 | 0.75 | GPR35 (0.54) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL1173852 | 0.75 | TDP1 (0.54) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL1036583 | 0.75 | TDP1 (0.45) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL2075134 | 0.75 | TDP1 (0.45) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 | |
| SCHEMBL7907932 | 0.75 | TDP1 (0.45) | TDP1HSD17B10TSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496296-A | Dolutegravir derivative with anti-tumor function and preparation method thereof | 河南师范大学 | 2023-07-28 | — | — | CN | claimed |
| CN-115746022-A | Preparation method and application of caspovir derivative | 河南科技大学 | 2023-03-07 | — | — | CN | claimed |
| CN-111848548-A | 5-substituted-1, 3, 4-thiadiazole Schiff base derivative and preparation method and application thereof | 天津科技大学 | 2020-10-30 | — | — | CN | claimed |
| CN-105622483-B | A kind of synthetic method of 4- nitroindoline | 苏州艾缇克药物化学有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109053534-A | A kind of preparation method of medicine intermediate 4- nitroindoline | 苏州盖德精细材料有限公司 | 2018-12-21 | — | — | CN | claimed |
| EP-3380457-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | Hangzhou Jennifer Biotech Co., Ltd. (CN) | 2018-10-03 | — | — | EP | claimed |
| US-20180244637-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | HANGZHOU JENNIFER BIOTECH CO., LTD. (CN) | 2018-08-30 | — | — | US | claimed |
| WO-2017080443-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | HANGZHOU JENNIFER BIOTECH CO., LTD. (CN) | 2017-05-18 | — | — | WO | claimed |
| CN-105622483-A | Synthesis method of 4-nitroindole | ITIC MEDCHEM CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-103396349-B | Acyl thiourea compound containing 1-methyl cyclohexyl as well as preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2014-12-17 | — | — | CN | claimed |
| EP-0025190-B1 | CHROMOGENIC COMPOUNDS AND THEIR USE AS ENZYMATIC SUBSTRATES | BEHRINGWERKE Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | claimed |
| US-4244865-A | α hydroxy tripeptide substrates | ABBOTT LABORATORIES (US) | 1981-01-13 | — | — | US | claimed |
| US-4219497-A | Chromogenic substrates | ABBOTT LABORATORIES (US) | 1980-08-26 | — | — | US | claimed |
| US-4217269-A | FOR SPECTROPHOTOMETRIC MEASUREMENT OF PROTEOLYTIC ENZYMES | ABBOTT LABORATORIES (US) | 1980-08-12 | — | — | US | claimed |
| US-4072576-A | Method for studying enzymatic and other biochemical reactions | AB KABI (SW) | 1978-02-07 | — | — | US | claimed |
| US-4060623-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | claimed |
| US-4038404-A | 1,2,4-TRIAZOLE ANTIMYCOTIC COMPOSITIONS AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | claimed |
| US-4036966-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-4036967-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-4010162-A | Substituted phenanthroline pigments | ALLIED CHEMICAL CORPORATION (US) | 1977-03-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180244637-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | TST, MPST, SQOR | TDP1 1942/4885HSD17B10 849/4885TSHR 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.