Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872313 | 0.90 | NPC1 (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| Naphthalene SCHEMBL9872543 | 0.87 | RAB9A (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL10950078 | 0.78 | RAB9A (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL5417312 | 0.78 | NPC1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL29813370 | 0.77 | NPC1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL108807 | 0.77 | NPC1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL9871694 | 0.77 | ALDH1A1 (0.38) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL2230003 | 0.77 | NPC1 (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL9870748 | 0.76 | VCAM1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL9788130 | 0.75 | NPC1 (0.68) | NPC1RAB9AALDH1A1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030731-A | Substituted benzotriazoles; storage stability; lacquers | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0180548-B1 | COATINGS STABILIZED AGAINST THE ACTION OF LIGHT | CIBA-GEIGY AG (CH) | 1989-06-28 | — | — | EP | disclosed |
| US-4775707-A | BLOCKED BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0180548-A2 | Coatings stabilized against the action of light | CIBA-GEIGY AG (CH) | 1986-05-07 | — | — | EP | disclosed |