Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593219 | 0.95 | VCAM1 (0.39) | VCAM1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9872313 | 0.86 | NPC1 (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9879793 | 0.84 | VCAM1 (0.36) | VCAM1SMN1; SMN2HPGD | |
| SCHEMBL9870052 | 0.83 | ALDH1A1 (0.35) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| Naphthalene SCHEMBL9872543 | 0.83 | RAB9A (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9871470 | 0.82 | RXRA (0.36) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5417312 | 0.82 | NPC1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9872532 | 0.81 | L3MBTL1 (0.43) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 | |
| SCHEMBL28022693 | 0.81 | NPC1 (0.38) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3537498 | 0.79 | HTT (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030731-A | Substituted benzotriazoles; storage stability; lacquers | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| US-4775707-A | BLOCKED BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1988-10-04 | — | — | US | disclosed |