Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061879 | 0.68 | SIGMAR1 (0.39) | MAPTKDM4E | |
| SCHEMBL4001774 | 0.68 | MEN1 (0.52) | MAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11553849 | 0.66 | MEN1 (0.50) | MAPTGAAKDM4ELMNA | |
| SCHEMBL8493961 | 0.65 | MEN1 (0.42) | NPC1MAPTPOLBGAAKDM4E | |
| SCHEMBL8539384 | 0.65 | HTR2C (0.47) | MAPTGAAKDM4ELMNA | |
| SCHEMBL11164098 | 0.64 | TLR4 (0.53) | TLR4NPC1MAPTKDM4E | |
| Formamide SCHEMBL11551135 | 0.64 | MEN1 (0.44) | MAPTLMNA | |
| SCHEMBL4905747 | 0.64 | DDB1 (0.40) | NPC1MAPTLMNASMN1; SMN2IDO1 | |
| SCHEMBL27582656 | 0.63 | CHRNB4 (0.37) | GAACCKBRKCNH2 | |
| SCHEMBL2639368 | 0.63 | CCKBR (0.33) | GAAKDM4ECCKBRSMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997831-A | Antagonists of 5-hydroxytryptamine receptors | GLAXO GROUP LIMITED (GB) | 1991-03-05 | — | — | US | disclosed |