Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11553849 | 0.98 | MEN1 (0.50) | MEN1KMT2ACYP3A4CYP2D6TAAR1 | |
| Formamide SCHEMBL11551135 | 0.89 | MEN1 (0.44) | MEN1KMT2ACYP3A4CYP2D6TAAR1 | |
| SCHEMBL11516181 | 0.85 | SLC6A2 (0.44) | — | |
| SCHEMBL8540865 | 0.85 | ESR2 (0.41) | MEN1KMT2ACYP3A4CYP2D6TAAR1 | |
| SCHEMBL5871368 | 0.85 | PRCP (0.42) | MEN1KMT2ACYP3A4CYP2D6MAPT | |
| SCHEMBL8543734 | 0.82 | HTR2A (0.46) | MEN1KMT2ACYP3A4CYP2D6KDM4E | |
| SCHEMBL8540456 | 0.81 | PAX8 (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6587573 | 0.81 | SLC6A3 (0.48) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL8485182 | 0.81 | DRD2 (0.41) | MEN1KMT2AKIF11DRD1DRD5 | |
| SCHEMBL1045807 | 0.80 | PDGFRA (0.41) | MEN1KMT2ACYP3A4CYP2D6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | claimed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | claimed |
| US-4153789-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-05-08 | — | — | US | claimed |
| US-4138494-A | ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-02-06 | — | — | US | claimed |
| US-4080330-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1978-03-21 | — | — | US | claimed |
| CN-116546990-B | CD73 inhibitor and pharmaceutical application thereof | RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-114539340-B | CD73 inhibitor and pharmaceutical application thereof | 润佳（苏州）医药科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20240024346-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2024-01-25 | — | — | US | disclosed |
| US-20240024346-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2024-01-25 | — | — | US | disclosed |
| US-20240024346-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2024-01-25 | — | — | US | disclosed |
| EP-4251633-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| US-20230295213-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-0721949-A1 | INDOLINE COMPOUND AND 5-HT 3? RECEPTOR ANTAGONIST CONTAINING THE SAME AS ACTIVE INGREDIENT | TOKYO TANABE COMPANY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0287196-B1 | Indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1994-11-23 | — | — | EP | disclosed |
| US-4920127-A | TREATMENT OF MIGRAINE, TRIGEMINAL NEURALGIA | BEECHAM GROUP P.L.C. (GB) | 1990-04-24 | — | — | US | disclosed |
| EP-0287196-A1 | Indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-10-19 | — | — | EP | disclosed |
| US-4153789-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-05-08 | — | — | US | disclosed |
| US-4138494-A | ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-02-06 | — | — | US | disclosed |
| US-4138494-A | ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-02-06 | — | — | US | disclosed |
| US-4080330-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295213-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | ENTPD5, NT5E, ENTPD1 | MEN1 1633/4885KMT2A 2779/4885CYP3A4 1184/4885 |
| US-20240024346-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | ENTPD5, NT5E, ENTPD1 | MEN1 1633/4885KMT2A 2779/4885CYP3A4 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.