Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270081 | 0.91 | SIGMAR1 (0.51) | CYP1A2SIGMAR1HTR1APARP1DRD2 | |
| Hydrochloric Acid SCHEMBL9871842 | 0.86 | SIGMAR1 (0.55) | SIGMAR1HTR1APARP1DRD2KMT2A | |
| Cadaverine Tartrate SCHEMBL9870835 | 0.86 | PARP1 (0.45) | SIGMAR1PARP1 | |
| Hydrochloric Acid SCHEMBL9870487 | 0.83 | SIGMAR1 (0.57) | CYP1A2SIGMAR1HTR1APARP1DRD2 | |
| SCHEMBL9872440 | 0.82 | PARP1 (0.52) | SIGMAR1HTR1APARP1DRD2DRD4 | |
| Cadaverine Tartrate SCHEMBL7270386 | 0.80 | CYP1A2 (0.46) | CYP1A2SIGMAR1HTR1ADRD2DRD4 | |
| Cadaverine Tartrate SCHEMBL9872353 | 0.80 | MAPT (0.47) | CYP1A2HTR1ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9871774 | 0.80 | SIGMAR1 (0.49) | SIGMAR1PARP1DRD2DRD4DRD3 | |
| SCHEMBL10333960 | 0.79 | DRD4 (0.49) | SIGMAR1HTR1APARP1DRD2DRD4 | |
| Cadaverine Tartrate SCHEMBL9870596 | 0.78 | HTR1A (0.45) | CYP1A2HTR1APARP1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071864-A | Administering for high blood pressure and central nervous syst em disorders | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |