Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9870484 | 0.86 | CYP1A2 (0.46) | PARP1SIGMAR1 | |
| SCHEMBL10333960 | 0.85 | DRD4 (0.49) | PARP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9870487 | 0.77 | SIGMAR1 (0.57) | PARP1SIGMAR1 | |
| SCHEMBL7270081 | 0.76 | SIGMAR1 (0.51) | PARP1SIGMAR1 | |
| Cadaverine Tartrate SCHEMBL9870829 | 0.75 | HRH2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL9870813 | 0.75 | SIGMAR1 (0.47) | PARP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9147375 | 0.73 | ALDH1A1 (0.47) | PARP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9871842 | 0.72 | SIGMAR1 (0.55) | PARP1SIGMAR1 | |
| Cadaverine Tartrate SCHEMBL9871896 | 0.71 | HTR1A (0.47) | SIGMAR1 | |
| SCHEMBL10332834 | 0.71 | SIGMAR1 (0.53) | PARP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071864-A | Administering for high blood pressure and central nervous syst em disorders | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |