2-Phenylbenzo[D]Thiazole

2-Phenylbenzo[D]Thiazole

SCHEMBL987060

CC(=O)/C=C(/C)O.[Ir].c1ccc(-c2nc3ccccc3s2)cc1.c1ccc(-c2nc3ccccc3s2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.55
KDM4E B2RXH2 7/20 0.55
NPC1 O15118 6/20 0.55
SMN1; SMN2 Q16637 6/20 0.55
MAPT P10636 4/20 0.55
GAA P10253 3/20 0.54
LMNA P02545 3/20 0.54
GLA P06280 2/20 0.54
ALDH1A1 P00352 1/20 0.54
PKM P14618 1/20 0.54
NFKB1 P19838 3/20 0.52
NFKB2 Q00653 3/20 0.52
RELA Q04206 3/20 0.52
MMP9 P14780 2/20 0.52
MMP8 P22894 2/20 0.52
MMP2 P08253 1/20 0.52
MMP13 P45452 1/20 0.52
TP53 P04637 3/20 0.51
APP P05067 3/20 0.50
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylbenzo[D]Thiazole SCHEMBL17022410 0.86 RAB9A (0.53) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL27624697 0.83 KDM4E (0.65) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL7090672 0.83 KDM4E (0.65) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL29928313 0.82 RAB9A (0.72) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL2453217 0.82 RAB9A (0.72) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL3371957 0.82 RAB9A (0.72) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL27607988 0.82 RAB9A (0.72) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.80 RAB9A (0.75) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL30988131 0.80 RAB9A (0.75) RAB9AKDM4ENPC1SMN1; SMN2MAPT
2-Phenylbenzo[D]Thiazole SCHEMBL29986751 0.78 RAB9A (0.72) RAB9AKDM4ENPC1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1374320-B1 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES UNIV PRINCETON (US) 2020-05-06 EP claimed
EP-2276084-A1 Materials and devices for blue phosphorescence based organic light emitting diodes The Trustees of Princeton University (US) 2011-01-19 EP claimed
US-7294849-B2 Materials and devices for blue phosphorescence based organic light emitting diodes THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2007-11-13 US claimed
EP-1374320-A4 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES UNIV PRINCETON (US) 2007-04-18 EP claimed
US-20040155238-A1 Materials and devices for blue phosphorescence based organic light emitting diodes NATIONAL SCIENCE FOUNDATION 2004-08-12 US claimed
EP-1374320-A2 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES The Trustees of Princeton University (US) 2004-01-02 EP claimed
WO-2002074015-A2 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-09-19 WO claimed
EP-2278637-B2 Complexes of form L2MX UNIV PRINCETON (US) 2021-06-09 EP disclosed
EP-1374320-B1 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES UNIV PRINCETON (US) 2020-05-06 EP disclosed
US-10629827-B2 Organometallic complexes as phosphorescent emitters in organic LEDs THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2020-04-21 US disclosed
EP-1933395-B2 Complexes of form L2IrX UNIV PRINCETON (US) 2019-08-07 EP disclosed
EP-3379591-A1 COMPLEXES OF FORM L2MX The Trustees of Princeton University (US) 2018-09-26 EP disclosed
EP-2911211-B1 COMPLEXES OF FORM L2MX UNIV PRINCETON (US) 2018-05-02 EP disclosed
EP-1374320-A2 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES The Trustees of Princeton University (US) 2004-01-02 EP disclosed
EP-1252803-A4 COMPLEXES OF FORM L 2?MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS UNIV PRINCETON (US) 2003-04-16 EP disclosed
US-20030017361-A1 Organometallic complexes as phosphorescent emitters in organic LEDs THOMPSON MARK E (US) 2003-01-23 US disclosed
EP-1252803-A1 COMPLEXES OF FORM L 2?MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-10-30 EP disclosed
WO-2002074015-A2 MATERIALS AND DEVICES FOR BLUE PHOSPHORESCENCE BASED ORGANIC LIGHT EMITTING DIODES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-09-19 WO disclosed
US-20020034656-A1 Organometallic complexes as phosphorescent emitters in organic LEDs THE UNIVERSITY OF SOUTHERN CALIFORNIA 2002-03-21 US disclosed
WO-2001041512-A1 COMPLEXES OF FORM L2MX AS PHOSPHORESCENT DOPANTS FOR ORGANIC LEDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2001-06-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10629827-B2 Organometallic complexes as phosphorescent emitters in organic LEDs MLX, L1CAM, POU5F1 RAB9A 3330/4885KDM4E 3894/4885NPC1 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.